Can we forecast induction failure in acute myeloid leukemia?
نویسندگان
چکیده
منابع مشابه
acute myeloid leukemia (aml): the role of intensive induction chemotherapy
intensive induction therapy-in acute myeloid leukemia (aml), as in some other systemic malignancies- is a strategy fundamentally different from post-remission strategies. approaches like consolidation treatment, prolonged mainte nance, and autologous or allogeneic transplantation in the first remission are directed against minimal residual disease with a malignant cell population having survive...
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MicroRNAs are small, non-coding sequences that regulate gene expression by inducing degradation or translational inhibition of target mRNAs. These molecules control many intracellular physiological and pathological processes.Abnormal expression of these moleculs has been described in different cancers including hematopoietic cancers. According to the type of cancer and the stage, miRNA’s expres...
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* Especialista em Pediatria e em Cancerologia, com área de atuação em Oncologia Pediátrica. Coordenadora da Unidade de Oncologia Pediátrica do Hospital São Rafael, Fundação Monte Tabor. Chefe do Serviço Dr. Jorge Bahia de Carvalho da Sociedade de Oncologia da Bahia (ONCO). Membro do Conselho Acadêmico da Sociedade Brasileira de Pediatria. A Oncologia Pediátrica é a subespecialidade que mais sof...
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Background: Interaction between killer cell immunoglobulin-like receptors (KIR) and human leukocyte antigen (HLA) class I molecules is important for regulation of natural killer (NK) cell function. Objective: The aim of this study was to investigate the impact of compound KIR-HLA genotype on susceptibility to acute leukemia. Methods: Cohorts of Iranian patients with acute myeloid leukemia (AML;...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2018
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.2018.187575